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| Thomas Ostenfeld Larsen Lektor |
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DTU Systembiologi
Institut for Systembiologi
Center for Microbial Biotechnology, Natural Product Chemistry
Danmarks Tekniske Universitet
Søltofts Plads
Bygning 221, rum 126
2800 Kgs. Lyngby
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Naturstoffer. Skimmelsvamp. Thomas Ostenfeld Larsen (TOL) forsker i naturstofkemi fra
skimmelsvampe og andre mikroorganismer. TOL beskæftiger sig med de
naturstoffer der udskilles fra svampe, og fokuserer særligt på at
opdage helt nye stoffer. I forlængelse heraf koncenterer TOL sig om
disse naturstoffers anvendelsesmuligheder, til eksempelvis at
fremstille antibiotika og anticancer stoffer. TOL beskæftiger sig
også med naturstoffers sundhedsskadelige og kræftfremkaldende
virkning. Naturstoffer fra
mikroorganismer Thomas Ostenfeld Larsen
forsker i naturstofkemi fra skimmelsvampe og andre
mikroorganismer. Naturstoffer er små organiske molekyler, som
udskilles fra svampe og som ofte er bioaktive. Det betyder, at de
kan have gavnlige effekter, der kan udskilles i fødevarer eller
bruges til at fremstille nye former for antibiotika eller
anticancer stoffer og et fokus er således at opdage helt nye
stoffer. Naturstoffer besidder dog ikke kun gavnlige effekter og
kan i de rigtige mængder og koncentrationer være generelt
sundhedsskadelige og kræftfremkaldende.
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Year |
Andersen, Mikael Rørdam ; Nielsen, Jakob Blæsbjerg ; Klitgaard, Andreas ; Petersen, Lene Maj ; Zachariasen, Mia ; Hansen, Tilde J ; Holberg Blicher, Lene ; Gotfredsen, Charlotte Held ; Larsen, Thomas Ostenfeld ; Nielsen, Kristian Fog ; Mortensen, Uffe Hasbro
in journal: National Academy of Sciences. Proceedings (ISSN: 0027-8424) (DOI: http://dx.doi.org/10.1073/pnas.1205532110), vol: 110, issue: 1, pages: E99-E107, 2013
Type:
Journal article - Journal article
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2013 |
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in journal: Fungal Biology (ISSN: 1878-6146) (DOI: http://dx.doi.org/10.1016/j.funbio.2011.11.008), vol: 116, issue: 2, pages: 249-260, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Journal of Medicinal Chemistry (ISSN: 0022-2623) (DOI: http://dx.doi.org/10.1021/jm200835c), vol: 55, issue: 2, pages: 652-660, 2012
Type:
Journal article - Journal article
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2012 |
Jakobsen, Tim Holm ; Bragason, Steinn Kristinn ; Phipps, Richard Kerry ; Christensen, Louise Dahl ; van Gennip, Maria ; Alhede, Morten ; Skindersoe, Mette ; Larsen, Thomas Ostenfeld ; Høiby, Niels ; Bjarnsholt, Thomas ; Givskov, Michael
in journal: Applied and Environmental Microbiology (ISSN: 0099-2240) (DOI: http://dx.doi.org/10.1128/AEM.05992-11), vol: 78, issue: 7, pages: 2410-2421, 2012
Type:
Journal article - Journal article
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2012 |
O'Hanlon, Karen A. ; Gallagher, Lorna ; Schrettl, Markus ; Jöchl, Christoph ; Kavanagh, Kevin ; Larsen, Thomas Ostenfeld ; Doyle, Sean
in journal: Applied and Environmental Microbiology (ISSN: 0099-2240) (DOI: http://dx.doi.org/10.1128/AEM.07249-11), vol: 78, issue: 9, pages: 3166-3176, 2012
Type:
Journal article - Journal article
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2012 |
Jakobsen, Tim Holm ; van Gennip, Maria ; Phipps, Richard Kerry ; Shanmugham, M Sundaram ; Christensen, Louise Dahl ; Alhede, Morten ; Skindersoe, Mette Eline ; Rasmussen, Thomas Bovbjerg ; Friedrich, Karlheinz ; Uthe, Friedrich ; Jensen, Peter Østrup ; Moser, Claus Ernst ; Nielsen, Kristian Fog ; Eberl, Leo ; Larsen, Thomas Ostenfeld ; Tanner, David Ackland ; Høiby, Niels ; Bjarnsholt, Thomas ; Givskov, Michael
in journal: Antimicrobial Agents and Chemotherapy (ISSN: 0066-4804) (DOI: http://dx.doi.org/10.1128/AAC.05919-11), vol: 56, issue: 5, pages: 2314-2325, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Applied and Environmental Microbiology (ISSN: 0099-2240) (DOI: http://dx.doi.org/10.1128/AEM.07955-11), vol: 78, issue: 14, pages: 4908-4913, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Planta Medica (ISSN: 0032-0943) (DOI: http://dx.doi.org/10.1055/s-0032-1320755), vol: 78, issue: 11, pages: 1159-1160, 2012
Type:
Journal article - Journal article
Presented at:
International Congress on Natural Products Research on Global Change, Natural Products and Human Health, New York City, NY
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2012 |
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in journal: Planta Medica (ISSN: 0032-0943) (DOI: http://dx.doi.org/10.1055/s-0032-1320343), vol: 78, issue: 11, pages: 1069-1069, 2012
Type:
Conference abstract in journal - Conference abstract in journal
Presented at:
International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF, New York, NY
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2012 |
Nielsen, Jakob Blæsbjerg ; Klejnstrup, Marie Louise ; Khorsand-Jamal, Paiman ; Holm, Dorte Koefoed ; Nielsen, Michael Lynge ; Kabat, Anna Monika ; Rank, Christian ; Gotfredsen, Charlotte Held ; Larsen, Thomas Ostenfeld ; Mortensen, Uffe Hasbro
in journal: Planta Medica (ISSN: 0032-0943) (DOI: http://dx.doi.org/10.1055/s-0032-1320546), vol: 78, issue: 11, pages: 1113-1113, 2012
Type:
Conference abstract in journal - Conference abstract in journal
Presented at:
International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF, New York, NY
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2012 |
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in journal: Planta Medica (ISSN: 0032-0943) (DOI: http://dx.doi.org/10.1055/s-0032-1320745), vol: 78, issue: 11, pages: 1158-1158, 2012
Type:
Conference abstract in journal - Conference abstract in journal
Presented at:
International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF, New York, NY
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2012 |
Larsen, Thomas Ostenfeld ; Givskov, Michael Christian ; Bjarnsholt, Thomas ; Jakobsen, Tim Holm ; Christensen, Louise Dahl ; Shanmugham, Meenakshi Sundaram ; Phipps, Richard Kerry ; Tanner, David Ackland ; Høiby, Niels ; Jensen, Peter Østrup
Type:
Patent - Patent
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2012 |
Raab, Marc S. ; Breitkreutz, Iris ; Anderhub, Simon ; Rønnest, Mads Holger ; Leber, Blanka ; Larsen, Thomas Ostenfeld ; Weiz, Ludmila ; Konotop, Gleb ; Hayden, Patrick J. ; Podar, Klaus ; Fruehauf, Johannes ; Nissen, Felix ; Mier, Walter ; Haberkorn, Uwe ; Ho, Anthony D. ; Goldschmidt, Hartmut ; Anderson, Kenneth C. ; Clausen, Mads Hartvig ; Krämer, Alwin
in journal: Cancer Research (ISSN: 0008-5472) (DOI: http://dx.doi.org/10.1158/0008-5472.CAN-12-2026), vol: 72, issue: 20, pages: 5374-5385, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Metabolites (ISSN: 2218-1989) (DOI: http://dx.doi.org/10.3390/metabo2010039), vol: 2, pages: 39-56, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Metabolites (ISSN: 2218-1989) (DOI: http://dx.doi.org/10.3390/metabo2010214), vol: 2, pages: 214-220, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Marine Drugs (ISSN: 1660-3397) (DOI: http://dx.doi.org/10.3390/md10112584), vol: 10, issue: 11, pages: 2584-2595, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Metabolites (ISSN: 2218-1989) (DOI: http://dx.doi.org/10.3390/metabo2010100), vol: 2, issue: 1, pages: 100-133, 2012
Type:
Journal article - Journal article
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2012 |
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Type:
Ph.d. thesis - Ph.d. thesis
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2012 |
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Type:
Ph.d. thesis - Ph.d. thesis
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2012 |
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Type:
Conference abstract for conference - Conference abstract for conference
Presented at:
Directing Biosynthesis III, Nottingham
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2012 |
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