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Title: NetAcet: prediction of N-terminal acetylation sites
Type: Journal articleJournal article
Participant(s):
Author:  Kiemer, Lars (Cwisno: 10309)
Technical University of Denmark

Author:  Bendtsen, Jannick Dyrløv (Cwisno: 9406)
Technical University of Denmark

Author:  Blom, Nikolaj (Cwisno: 50261)
Technical University of Denmark
Email:

Abstract: Summary: We present here a neural network based method for prediction of N-terminal acetylation-by far the most abundant post-translational modification in eukaryotes. The method was developed on a yeast dataset for N-acetyltransferase A (NatA) acetylation, which is the type of N-acetylation for which most examples are known and for which orthologs have been found in several eukaryotes. We obtain correlation coefficients close to 0.7 on yeast data and a sensitivity up to 74% on mammalian data, suggesting that the method is valid for eukaryotic NatA orthologs.
Published: in journal: Bioinformatics (ISSN: 1367-4803), vol: 21, issue: 7, pages: 1269-1270, 2005
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